Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

Sepsis is one of the most prevalent diseases in the world. The development of cardiac dysfunction in sepsis results in an increase of mortality. It is known that Bruton's tyrosine kinase (BTK) plays a role in toll-like receptor signaling and NLRP3 inflammasome activation, two key components in...

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Publicat a:Front Immunol
Autors principals: O'Riordan, Caroline E., Purvis, Gareth S. D., Collotta, Debora, Chiazza, Fausto, Wissuwa, Bianka, Al Zoubi, Sura, Stiehler, Lara, Martin, Lukas, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph
Format: Artigo
Idioma:Inglês
Publicat: Frontiers Media S.A. 2019
Matèries:
Immunology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743418/
https://ncbi.nlm.nih.gov/pubmed/31552054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02129
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