Bruton's Tyrosine Kinase Inhibition Attenuates the Cardiac Dysfunction Caused by Cecal Ligation and Puncture in Mice

Sepsis is one of the most prevalent diseases in the world. The development of cardiac dysfunction in sepsis results in an increase of mortality. It is known that Bruton's tyrosine kinase (BTK) plays a role in toll-like receptor signaling and NLRP3 inflammasome activation, two key components in...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: O'Riordan, Caroline E., Purvis, Gareth S. D., Collotta, Debora, Chiazza, Fausto, Wissuwa, Bianka, Al Zoubi, Sura, Stiehler, Lara, Martin, Lukas, Coldewey, Sina M., Collino, Massimo, Thiemermann, Christoph
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Immunology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743418/
https://ncbi.nlm.nih.gov/pubmed/31552054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.02129
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