Parallel Accumulation of Tumor Hyaluronan, Collagen, and Other Drivers of Tumor Progression

PURPOSE: The tumor microenvironment (TME) evolves to support tumor progression. One marker of more aggressive malignancy is hyaluronan (HA) accumulation. Here, we characterize biological and physical changes associated with HA-accumulating (HA-high) tumors. EXPERIMENTAL DESIGN: We used immunohistoch...

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Detalhes bibliográficos
Publicado no:Clin Cancer Res
Main Authors: Li, Xiaoming, Shepard, Michael H., Cowell, Jessica A., Zhao, Chunmei, Osgood, Ryan J., Rosengren, Sanna, Blouw, Barbara, Garrovillo, Sheryl A., Pagel, Mark D., Whatcott, Clifford J., Han, Haiyong, Von Hoff, Daniel D., Taverna, Darin M., LaBarre, Michael J., Maneval, Daniel C., Thompson, Curtis B.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743334/
https://ncbi.nlm.nih.gov/pubmed/30084839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1078-0432.CCR-17-3284
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