ABCC6–Mediated ATP Secretion by the Liver Is the Main Source of the Mineralization Inhibitor Inorganic Pyrophosphate in the Systemic Circulation—Brief Report

OBJECTIVE—: Mutations in ABCC6 underlie the ectopic mineralization disorder pseudoxanthoma elasticum (PXE) and some forms of generalized arterial calcification of infancy, both of which affect the cardiovascular system. Using cultured cells, we recently showed that ATP-binding cassette subfamily C m...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Arterioscler Thromb Vasc Biol
Egile Nagusiak: Jansen, Robert S., Duijst, Suzanne, Mahakena, Sunny, Sommer, Daniela, Szeri, Flóra, Váradi, András, Plomp, Astrid, Bergen, Arthur A., Oude Elferink, Ronald PJ., Borst, Piet, Koen van de, Wetering
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2014
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6743317/
https://ncbi.nlm.nih.gov/pubmed/24969777
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1161/ATVBAHA.114.304017
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