PAR2 controls cholesterol homeostasis and lipid metabolism in nonalcoholic fatty liver disease

OBJECTIVE: Increases in hepatic and plasma cholesterol occur in patients with nonalcoholic fatty liver disease (NAFLD), although the reason for this is not well understood. We investigated whether Protease-Activated Receptor 2 (PAR2) plays a role in cholesterol and lipid homeostasis in NAFLD. METHOD...

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Détails bibliographiques
Publié dans:Mol Metab
Auteurs principaux: Rana, Rajashree, Shearer, Andrew M., Fletcher, Elizabeth K., Nguyen, Nga, Guha, Srijoy, Cox, Daniel H., Abdelmalek, Manal, Wang, Ying, Baleja, James D., Covic, Lidija, Kuliopulos, Athan
Format: Artigo
Langue:Inglês
Publié: Elsevier 2019
Sujets:
Original Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742970/
https://ncbi.nlm.nih.gov/pubmed/31668396
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2019.08.019
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