Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes

Lentiviral vectors (LVs) are excellent tools for gene transfer into mammalian cells. It is noteworthy that the first gene therapy treatment using LVs was approved for commercialization in 2017. The G glycoprotein from rhabdovirus vesicular stomatitis virus (VSV-G) is the glycoprotein most used to ps...

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Detalhes bibliográficos
Publicado no:Mol Ther Methods Clin Dev
Main Authors: Tomás, Hélio A., Mestre, Daniel A., Rodrigues, Ana F., Guerreiro, Miguel R., Carrondo, Manuel J.T., Coroadinha, Ana Sofia
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Gene & Cell Therapy 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742969/
https://ncbi.nlm.nih.gov/pubmed/31528654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.08.001
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