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Improved GaLV-TR Glycoproteins to Pseudotype Lentiviral Vectors: Impact of Viral Protease Activity in the Production of LV Pseudotypes

Lentiviral vectors (LVs) are excellent tools for gene transfer into mammalian cells. It is noteworthy that the first gene therapy treatment using LVs was approved for commercialization in 2017. The G glycoprotein from rhabdovirus vesicular stomatitis virus (VSV-G) is the glycoprotein most used to ps...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Mol Ther Methods Clin Dev
Päätekijät: Tomás, Hélio A., Mestre, Daniel A., Rodrigues, Ana F., Guerreiro, Miguel R., Carrondo, Manuel J.T., Coroadinha, Ana Sofia
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society of Gene & Cell Therapy 2019
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742969/
https://ncbi.nlm.nih.gov/pubmed/31528654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtm.2019.08.001
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