SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production

Lentiviral vectors (LVs) derived from HIV-1 are widely used in gene therapy, with several approved products. However, establishing stable cell lines for constitutive LV production remains a challenge due to the cytotoxicity of vector proteins, including some envelope glycoproteins used for pseudotyp...

Descrizione completa

Dettagli Bibliografici

Autori principali:	Rodrigo José Nogueira, Ana Filipa Rodrigues, Daniel Alexandre Mestre, Ana Sofia Coroadinha
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2025-12-01
Serie:	Molecular Therapy: Methods & Clinical Development
Soggetti:	lentiviral vectors stable cell lines constitutive lentiviral vector production fusogenic envelope glycoprotein syncytia receptor knockout
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2329050125002141
Tags:	Aggiungi Tag Nessun Tag, puoi essere il primo ad aggiungerne!!