Vpu-dependent block to incorporation of GaLV Env into lentiviral vectors

BACKGROUND: The gibbon ape leukemia virus (GaLV) Env protein mediates entry into a wide range of human cells and is frequently used to pseudotype retroviral vectors. However, an incompatibility exists between GaLV Env and lentiviral vectors that results in decreased steady-state levels of the mature...

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Autori principali: Christodoulopoulos, Ilias, Droniou-Bonzom, Magali E, Oldenburg, Jill E, Cannon, Paula M
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioMed Central 2010
Soggetti:
Research
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC2831008/
https://ncbi.nlm.nih.gov/pubmed/20102634
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-7-4
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