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Cerebrospinal Fluid and Brain Tissue Penetration of Tenofovir, Lamivudine, and Efavirenz in Postmortem Tissues with Cryptococcal Meningitis

The central nervous system (CNS) is a known HIV reservoir, yet little is known about drug exposure in the brain. Our primary objective was to quantify exposure of three common antiretrovirals in brain tissue and compare exposures to plasma and cerebrospinal fluid (CSF). We also sought to identify po...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Clin Transl Sci
Κύριοι συγγραφείς: Nicol, Melanie R., Pastick, Katelyn A., Taylor, Joneé, Namuju, Olivie C., Rhein, Joshua, Williams, Darlisha A., Meya, David B., Boulware, David R., Lukande, Robert
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: John Wiley and Sons Inc. 2019
Θέματα:
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742940/
https://ncbi.nlm.nih.gov/pubmed/31207069
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/cts.12661
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