Increased Sensitivity of Injured and Adjacent Uninjured Rat Primary Sensory Neurons to Exogenous Tumor Necrosis Factor-α after Spinal Nerve Ligation

Tumor necrosis factor-α (TNF) is upregulated after nerve injury, causes pain on injection, and its blockade reduces pain behavior resulting from nerve injury; thus it is strongly implicated in neuropathic pain. We investigated responses of intact and nerve-injured dorsal root ganglia (DRG) neurons t...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Schäfers, Maria, Lee, Doo H., Brors, Dominik, Yaksh, Tony L., Sorkin, Linda S.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
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ARTICLE
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6742101/
https://ncbi.nlm.nih.gov/pubmed/12684490
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-07-03028.2003
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