Impact of gabapentin on neuronal high voltage-activated Ca(2+) channel properties of injured-side axotomized and adjacent uninjured dorsal root ganglions in a rat model of spinal nerve ligation

The density and properties of ion channels in the injured axon and dorsal root ganglion (DRG) neuronal soma membrane change following nerve injury, which may result in the development of neuropathic pain. Gabapentin (GBP) is a drug for the first-line treatment of neuropathic pain. One of its therape...

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Detalhes bibliográficos
Publicado no:Exp Ther Med
Main Authors: Zhu, Minmin, Sun, Xiaodi, Chen, Xiaodong, Xiao, Hang, Duan, Manlin, Xu, Jianguo
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2017
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Articles
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5403705/
https://ncbi.nlm.nih.gov/pubmed/28450909
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/etm.2017.4071
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