Upregulation of Dorsal Root Ganglion α(2)δ Calcium Channel Subunit and Its Correlation with Allodynia in Spinal Nerve-Injured Rats

Peripheral nerve injury can lead to a persistent neuropathic pain state in which innocuous tactile stimulation elicits pain behavior (tactile allodynia). Spinal administration of the anticonvulsant gabapentin suppresses allodynia by an unknown mechanism. In vitro studies indicate that gabapentin bin...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Luo, Z. David, Chaplan, Sandra R., Higuera, Emiliano S., Sorkin, Linda S., Stauderman, Kenneth A., Williams, Mark E., Yaksh, Tony L.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2001
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6762626/
https://ncbi.nlm.nih.gov/pubmed/11245671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.21-06-01868.2001
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