Transient and Progressive Electrophysiological Alterations in the Corticostriatal Pathway in a Mouse Model of Huntington's Disease

Alterations in the corticostriatal pathway may precede symptomatology and striatal cell death in Huntington's disease (HD) patients. Here we examined spontaneous EPSCs in striatal medium-sized spiny neurons in slices from a mouse model of HD (R6/2). Spontaneous EPSC frequency was similar in you...

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Publié dans:J Neurosci
Auteurs principaux: Cepeda, Carlos, Hurst, Raymond S., Calvert, Christopher R., Hernández-Echeagaray, Elizabeth, Nguyen, Oanh K., Jocoy, Emily, Christian, Lindsey J., Ariano, Marjorie A., Levine, Michael S.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2003
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Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741903/
https://ncbi.nlm.nih.gov/pubmed/12574425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-03-00961.2003
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