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Differential Electrophysiological and Morphological Alterations of Thalamostriatal and Corticostriatal Projections in the R6/2 Mouse Model of Huntington’s Disease

Huntington’s disease (HD) is a fatal genetic disorder characterized by cell death of medium-sized spiny neurons (MSNs) in the striatum, traditionally attributed to excessive glutamate inputs and/or receptor sensitivity. While changes in corticostriatal projections have typically been studied in mous...

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Detalhes bibliográficos
Publicado no:Neurobiol Dis
Main Authors: Parievsky, Anna, Moore, Cindy, Kamdjou, Talia, Cepeda, Carlos, Meshul, Charles K., Levine, Michael S.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5675804/
https://ncbi.nlm.nih.gov/pubmed/28757327
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2017.07.020
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