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The Cellular Biochemistry of Cholesterol and Statins: Insights into the Pathophysiology and Therapy of Alzheimer's Disease

The causes of late onset Alzheimer disease (AD) are poorly understood. Although β‐amyloid (Aβ) is thought to play a critical role in the pathophysiology of AD, no genetic evidence directly ties Aβ to late onset AD. This suggests that the accumulation of Aβ and neurodegeneration associated with AD mi...

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Библиографические подробности
Опубликовано в: :CNS Drug Rev
Главные авторы: Wolozin, Benjamin, III, James Brown, Theisler, Catherine, Silberman, Simone
Формат: Artigo
Язык:Inglês
Опубликовано: Blackwell Publishing Ltd 2006
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741763/
https://ncbi.nlm.nih.gov/pubmed/15179443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2004.tb00009.x
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