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Cellular cholesterol homeostasis and Alzheimer’s disease
Alzheimer’s disease (AD) is the most common form of dementia in older adults. Currently, there is no cure for AD. The hallmark of AD is the accumulation of extracellular amyloid plaques composed of amyloid-β (Aβ) peptides (especially Aβ1-42) and neurofibrillary tangles, composed of hyperphosphorylat...
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| Publicado no: | J Lipid Res |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The American Society for Biochemistry and Molecular Biology
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5711498/ https://ncbi.nlm.nih.gov/pubmed/28298292 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R075630 |
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