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Cellular cholesterol homeostasis and Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia in older adults. Currently, there is no cure for AD. The hallmark of AD is the accumulation of extracellular amyloid plaques composed of amyloid-β (Aβ) peptides (especially Aβ1-42) and neurofibrillary tangles, composed of hyperphosphorylat...

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Detalles Bibliográficos
Publicado en:J Lipid Res
Main Authors: Chang, Ta-Yuan, Yamauchi, Yoshio, Hasan, Mazahir T., Chang, Catherine
Formato: Artigo
Idioma:Inglês
Publicado: The American Society for Biochemistry and Molecular Biology 2017
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711498/
https://ncbi.nlm.nih.gov/pubmed/28298292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R075630
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