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Cellular cholesterol homeostasis and Alzheimer’s disease

Alzheimer’s disease (AD) is the most common form of dementia in older adults. Currently, there is no cure for AD. The hallmark of AD is the accumulation of extracellular amyloid plaques composed of amyloid-β (Aβ) peptides (especially Aβ1-42) and neurofibrillary tangles, composed of hyperphosphorylat...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Lipid Res
Hauptverfasser: Chang, Ta-Yuan, Yamauchi, Yoshio, Hasan, Mazahir T., Chang, Catherine
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Biochemistry and Molecular Biology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5711498/
https://ncbi.nlm.nih.gov/pubmed/28298292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1194/jlr.R075630
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