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Development of the Nitrone‐Based Spin Trap Agent NXY‐059 to Treat Acute Ischemic Stroke

The only current FDA‐approved treatment for acute ischemic stroke is thrombolysis with tissue plasminogen activator (tPA). However, there are numerous shortcomings to tPA treatment including an increased incidence of intracerebral hemorrhage (ICH) and a short therapeutic window (3–6 h). In recent ye...

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Detalhes bibliográficos
Publicado no:CNS Drug Rev
Main Authors: Lapchak, Paul A., Araujo, Dalia M.
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2006
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741678/
https://ncbi.nlm.nih.gov/pubmed/14530797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1527-3458.2003.tb00252.x
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