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De-Risking of Stilbazulenyl Nitrone (STAZN), a Lipophilic Nitrone to Treat Stroke Using a Unique Panel of In Vitro Assays

In the present study, we used a comprehensive panel of in vitro assays to evaluate the efficacy and safety of stilbazulenyl nitrone (STAZN) as a lead compound to treat acute ischemic stroke. First, we measured neuroprotection in vitro using two different HT22 hippocampal nerve cell assays. Secondly,...

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Detalhes bibliográficos
Main Authors: Lapchak, Paul A., Schubert, David R., Maher, Pamela A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3191534/
https://ncbi.nlm.nih.gov/pubmed/22003372
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12975-011-0071-7
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