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Exosome-Derived miRNAs and Cellular miRNAs Activate Innate Immunity

Circulating exosome-containing small RNAs have been demonstrated in vitro to be taken up by recipient cells and to alter gene expression through RNA interference. Here, we show that exosomes purified from various cancer cell lines as well as gel-purified exosomal and cellular miRNAs can induce pro-i...

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Bibliografiske detaljer
Udgivet i:J Innate Immun
Main Authors: Mobergslien, Anne, Sioud, Mouldy
Format: Artigo
Sprog:Inglês
Udgivet: S. Karger AG 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741584/
https://ncbi.nlm.nih.gov/pubmed/23774807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351460
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