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Exosome-Derived miRNAs and Cellular miRNAs Activate Innate Immunity

Circulating exosome-containing small RNAs have been demonstrated in vitro to be taken up by recipient cells and to alter gene expression through RNA interference. Here, we show that exosomes purified from various cancer cell lines as well as gel-purified exosomal and cellular miRNAs can induce pro-i...

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Detalles Bibliográficos
Publicado en:J Innate Immun
Autores principales: Mobergslien, Anne, Sioud, Mouldy
Formato: Artigo
Lenguaje:Inglês
Publicado: S. Karger AG 2014
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741584/
https://ncbi.nlm.nih.gov/pubmed/23774807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351460
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