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Exosome-Derived miRNAs and Cellular miRNAs Activate Innate Immunity

Circulating exosome-containing small RNAs have been demonstrated in vitro to be taken up by recipient cells and to alter gene expression through RNA interference. Here, we show that exosomes purified from various cancer cell lines as well as gel-purified exosomal and cellular miRNAs can induce pro-i...

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Detalles Bibliográficos
Publicado en:J Innate Immun
Main Authors: Mobergslien, Anne, Sioud, Mouldy
Formato: Artigo
Idioma:Inglês
Publicado: S. Karger AG 2014
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741584/
https://ncbi.nlm.nih.gov/pubmed/23774807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000351460
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