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The Production of Amyloid β Peptide Is a Critical Requirement for the Viability of Central Neurons

The amyloid β peptide (Aβ) is a product of the sequential γ- and β-secretase cleavage of amyloid precursor protein. Inhibitors of secretase enzymes have been proposed as a potential therapeutic strategy in the treatment of Alzheimer's disease. Here, we investigate the effect of inhibiting these...

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Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Neurosci
Egile Nagusiak: Plant, Leigh D., Boyle, John P., Smith, Ian F., Peers, Chris, Pearson, Hugh A.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Society for Neuroscience 2003
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741264/
https://ncbi.nlm.nih.gov/pubmed/12843253
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-13-05531.2003
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