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The Production of Amyloid β Peptide Is a Critical Requirement for the Viability of Central Neurons
The amyloid β peptide (Aβ) is a product of the sequential γ- and β-secretase cleavage of amyloid precursor protein. Inhibitors of secretase enzymes have been proposed as a potential therapeutic strategy in the treatment of Alzheimer's disease. Here, we investigate the effect of inhibiting these...
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| Publicado en: | J Neurosci |
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| Autores principales: | , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Society for Neuroscience
2003
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6741264/ https://ncbi.nlm.nih.gov/pubmed/12843253 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-13-05531.2003 |
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