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Thrombin-Induced Microglial Activation Produces Degeneration of Nigral Dopaminergic Neurons In Vivo

The present study examined whether thrombin-induced microglial activation could contribute to death of dopaminergic neurons in the rat substantia nigra (SN) in vivo. Seven days after thrombin injection into the SN, tyrosine hydroxylase immunohistochemistry showed a significant loss of nigral dopamin...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Choi, Sang-H., Joe, Eun H., Kim, Seung U., Jin, Byung K.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2003
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741241/
https://ncbi.nlm.nih.gov/pubmed/12843292
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-13-05877.2003
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