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Thrombin-induced microglial activation contributes to the degeneration of nigral dopaminergic neurons in vivo
OBJECTIVE: To evaluate the role of thrombin-activated microglia in the neurodegeneration of nigral dopaminergic neurons in the rat substantia nigra (SN) in vivo. METHODS: After stereotaxic thrombin injection into unilateral SN of rats, immunostaining, reverse transcription polymerase chain reaction...
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| Publicado no: | Neurosci Bull |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5552513/ https://ncbi.nlm.nih.gov/pubmed/18369384 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12264-008-0066-x |
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