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The Position of the Fourth Segment of Domain 4 Determines Status of the Inactivation Gate in Na(+) Channels

The fourth segment of domain 4 (S4/D4) in Na(+) channels is a voltage sensor especially implicated in channel inactivation. Although there has been evidence that S4/D4 moves externally during membrane depolarization, whether (and if so, how) the movement leads to conformational changes of the inacti...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Yang, Ya-Chin, Kuo, Chung-Chin
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741210/
https://ncbi.nlm.nih.gov/pubmed/12832514
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-04922.2003
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