Functional Tolerance and Blockade of Long-Term Depression at Synapses in the Nucleus Accumbens after Chronic Cannabinoid Exposure

The rewarding properties of the psychoactive constituents of marijuana, termed “cannabinoids,” may reflect actions on synaptic transmission in the nucleus accumbens (NAc). Furthermore, long-term changes in these synapses may support the addictive process. Excitatory and inhibitory synapses are acute...

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Publicat a:J Neurosci
Autors principals: Hoffman, Alexander F., Oz, Murat, Caulder, Tara, Lupica, Carl R.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2003
Matèries:
Brief Communications
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741179/
https://ncbi.nlm.nih.gov/pubmed/12832502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-04815.2003
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