Functional Tolerance and Blockade of Long-Term Depression at Synapses in the Nucleus Accumbens after Chronic Cannabinoid Exposure

The rewarding properties of the psychoactive constituents of marijuana, termed “cannabinoids,” may reflect actions on synaptic transmission in the nucleus accumbens (NAc). Furthermore, long-term changes in these synapses may support the addictive process. Excitatory and inhibitory synapses are acute...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Hoffman, Alexander F., Oz, Murat, Caulder, Tara, Lupica, Carl R.
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2003
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Brief Communications
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6741179/
https://ncbi.nlm.nih.gov/pubmed/12832502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-12-04815.2003
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