Opposing actions of chronic Δ(9)-tetrahydrocannabinol and cannabinoid antagonists on hippocampal long-term potentiation

Memory deficits produced by marijuana arise partly via interaction of the psychoactive component, Δ(9)-tetrahydrocannabinol (Δ(9)-THC), with cannabinoid receptors in the hippocampus. Although cannabinoids acutely reduce glutamate release and block hippocampal long-term potentiation (LTP), a potentia...

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Autors principals: Hoffman, Alexander F., Oz, Murat, Yang, Ruiqin, Lichtman, Aron H., Lupica, Carl R.
Format: Artigo
Idioma:Inglês
Publicat: Cold Spring Harbor Laboratory Press 2007
Matèries:
Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC1828281/
https://ncbi.nlm.nih.gov/pubmed/17202425
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/lm.439007
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