The psychoactive plant cannabinoid, Δ(9)-tetrahydrocannabinol, is antagonized by Δ(8)- and Δ(9)-tetrahydrocannabivarin in mice in vivo

BACKGROUND AND PURPOSE: To follow up in vitro evidence that Δ(9)-tetrahydrocannabivarin extracted from cannabis (eΔ(9)-THCV) is a CB(1) receptor antagonist by establishing whether synthetic Δ(9)-tetrahydrocannabivarin (O-4394) and Δ(8)-tetrahydrocannabivarin (O-4395) behave as CB(1) antagonists in v...

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Detalhes bibliográficos
Main Authors: Pertwee, R G, Thomas, A, Stevenson, L A, Ross, R A, Varvel, S A, Lichtman, A H, Martin, B R, Razdan, R K
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2007
Assuntos:
Research Papers
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2189766/
https://ncbi.nlm.nih.gov/pubmed/17245367
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0707124
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