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Endogenous cannabinoids mediate long-term synaptic depression in the nucleus accumbens

Do endocannabinoids (eCBs) participate in long-term synaptic plasticity in the brain? Using pharmacological approaches and genetically altered mice, we show that stimulation of prelimbic cortex afferents at naturally occurring frequencies causes a long-term depression of nucleus accumbens glutamater...

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Detalhes bibliográficos
Main Authors: Robbe, David, Kopf, Manfred, Remaury, Anne, Bockaert, Joel, Manzoni, Olivier J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC123076/
https://ncbi.nlm.nih.gov/pubmed/12060781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.122149199
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