A Single In Vivo Exposure to Cocaine Abolishes Endocannabinoid-Mediated Long-Term Depression in the Nucleus Accumbens

In the nucleus accumbens (NAc), a key structure to the effects of all addictive drugs, presynaptic cannabinoid CB1 receptors (CB1Rs) and postsynaptic metabotropic glutamate 5 receptors (mGluR5s) are the principal effectors of endocannabinoid (eCB)-mediated retrograde long-term depression (LTD) (eCB-...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Fourgeaud, Lawrence, Mato, Susana, Bouchet, Delphine, Hémar, Agnès, Worley, Paul F., Manzoni, Olivier J.
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Behavioral/Systems/Cognitive
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729592/
https://ncbi.nlm.nih.gov/pubmed/15295029
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0671-04.2004
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