Mechanism of Toxicity in Rotenone Models of Parkinson's Disease

Exposure of rats to the pesticide and complex I inhibitor rotenone reproduces features of Parkinson's disease, including selective nigrostriatal dopaminergic degeneration and α-synuclein-positive cytoplasmic inclusions (Betarbet et al., 2000; Sherer et al., 2003). Here, we examined mechanisms o...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Sherer, Todd B., Betarbet, Ranjita, Testa, Claudia M., Seo, Byoung Boo, Richardson, Jason R., Kim, Jin Ho, Miller, Gary W., Yagi, Takao, Matsuno-Yagi, Akemi, Greenamyre, J. Timothy
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2003
Assuntos:
Cellular/Molecular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740985/
https://ncbi.nlm.nih.gov/pubmed/14645467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-34-10756.2003
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