Mechanism of Toxicity in Rotenone Models of Parkinson's Disease

Exposure of rats to the pesticide and complex I inhibitor rotenone reproduces features of Parkinson's disease, including selective nigrostriatal dopaminergic degeneration and α-synuclein-positive cytoplasmic inclusions (Betarbet et al., 2000; Sherer et al., 2003). Here, we examined mechanisms o...

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Dettagli Bibliografici
Pubblicato in:J Neurosci
Autori principali: Sherer, Todd B., Betarbet, Ranjita, Testa, Claudia M., Seo, Byoung Boo, Richardson, Jason R., Kim, Jin Ho, Miller, Gary W., Yagi, Takao, Matsuno-Yagi, Akemi, Greenamyre, J. Timothy
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
Soggetti:
Cellular/Molecular
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740985/
https://ncbi.nlm.nih.gov/pubmed/14645467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-34-10756.2003
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