Alzheimer's Presenilin 1 Mutations Impair Kinesin-Based Axonal Transport

Several lines of evidence indicate that alterations in axonal transport play a critical role in Alzheimer's disease (AD) neuropathology, but the molecular mechanisms that control this process are not understood fully. Recent work indicates that presenilin 1 (PS1) interacts with glycogen synthas...

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Bibliographische Detailangaben
Veröffentlicht in:J Neurosci
Hauptverfasser: Pigino, Gustavo, Morfini, Gerardo, Pelsman, Alejandra, Mattson, Mark P., Brady, Scott T., Busciglio, Jorge
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2003
Schlagworte:
Cellular/Molecular
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740780/
https://ncbi.nlm.nih.gov/pubmed/12805290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-11-04499.2003
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