Glycine Receptor Knock-In Mice and Hyperekplexia-Like Phenotypes: Comparisons with the Null Mutant

Strychnine-sensitive glycine receptors (GlyRs) inhibit neurotransmission in the spinal cord and brainstem. To better define the function of this receptor in vivo, we constructed a point mutation that impairs receptor function in the α(1)-subunit and compared these knock-in mice to oscillator (spd(ot...

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Pubblicato in:J Neurosci
Autori principali: Findlay, Geoffrey S., Phelan, Rachel, Roberts, Michael T., Homanics, Gregg E., Bergeson, Susan E., Lopreato, Gregory F., Mihic, S. John, Blednov, Yuri A., Harris, R. Adron
Natura: Artigo
Lingua:Inglês
Pubblicazione: Society for Neuroscience 2003
Soggetti:
Behavioral/Systems/Cognitive
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740502/
https://ncbi.nlm.nih.gov/pubmed/12954867
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.23-22-08051.2003
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