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Glutathione depletion‐induced chromosomal DNA fragmentation associated with apoptosis and necrosis

Chromosomal DNA and mitochondrial dysfunctions play a role on mammalian cell death induced by oxidative stress. The major biochemical dysfunction of chromosome is the presence of an ordered cleavage of the DNA backborn, which is separated and visualized as an electrophoretic pattern of fragments. Ox...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Cell Mol Med
1. Verfasser: Higuchi, Yoshihiro
Format: Artigo
Sprache:Inglês
Veröffentlicht: Blackwell Publishing Ltd 2007
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740256/
https://ncbi.nlm.nih.gov/pubmed/15601574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2004.tb00470.x
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