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Glutathione depletion‐induced chromosomal DNA fragmentation associated with apoptosis and necrosis

Chromosomal DNA and mitochondrial dysfunctions play a role on mammalian cell death induced by oxidative stress. The major biochemical dysfunction of chromosome is the presence of an ordered cleavage of the DNA backborn, which is separated and visualized as an electrophoretic pattern of fragments. Ox...

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Detalhes bibliográficos
Publicado no:J Cell Mol Med
Autor principal: Higuchi, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Publishing Ltd 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740256/
https://ncbi.nlm.nih.gov/pubmed/15601574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2004.tb00470.x
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