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Glutathione depletion‐induced chromosomal DNA fragmentation associated with apoptosis and necrosis

Chromosomal DNA and mitochondrial dysfunctions play a role on mammalian cell death induced by oxidative stress. The major biochemical dysfunction of chromosome is the presence of an ordered cleavage of the DNA backborn, which is separated and visualized as an electrophoretic pattern of fragments. Ox...

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Detalles Bibliográficos
Publicado en:J Cell Mol Med
Autor Principal: Higuchi, Yoshihiro
Formato: Artigo
Idioma:Inglês
Publicado: Blackwell Publishing Ltd 2007
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740256/
https://ncbi.nlm.nih.gov/pubmed/15601574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1582-4934.2004.tb00470.x
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