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Evolving Concept of Activity Cliffs

[Image: see text] Activity cliffs (ACs) are generally defined as pairs or groups of structurally similar compounds that are active against the same target but have large differences in potency. Accordingly, ACs capture chemical modifications that strongly influence biological activity. Therefore, th...

詳細記述

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書誌詳細
出版年:ACS Omega
主要な著者: Stumpfe, Dagmar, Hu, Huabin, Bajorath, Jürgen
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2019
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6740043/
https://ncbi.nlm.nih.gov/pubmed/31528788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02221
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