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Evolving Concept of Activity Cliffs
[Image: see text] Activity cliffs (ACs) are generally defined as pairs or groups of structurally similar compounds that are active against the same target but have large differences in potency. Accordingly, ACs capture chemical modifications that strongly influence biological activity. Therefore, th...
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| Publicado no: | ACS Omega |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical Society
2019
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6740043/ https://ncbi.nlm.nih.gov/pubmed/31528788 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b02221 |
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