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Rationalizing the Formation of Activity Cliffs in Different Compound Data Sets

[Image: see text] Activity cliffs are formed by structurally analogous compounds with large potency variations and are highly relevant for the exploration of discontinuous structure–activity relationships and compound optimization. So far, activity cliffs have mostly been studied on a case-by-case b...

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Detaylı Bibliyografya
Yayımlandı:ACS Omega
Asıl Yazarlar: Hu, Huabin, Stumpfe, Dagmar, Bajorath, Jürgen
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: American Chemical Society 2018
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC6644420/
https://ncbi.nlm.nih.gov/pubmed/31458921
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.8b01188
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