Long noncoding RNA GSTM3TV2 upregulates LAT2 and OLR1 by competitively sponging let-7 to promote gemcitabine resistance in pancreatic cancer

BACKGROUND: Chemoresistance is one of the main causes of poor prognosis in pancreatic cancer patients. Understanding the mechanisms implicated in chemoresistance of pancreatic cancer is critical to improving patient outcomes. Recent evidences indicate that the long noncoding RNAs (lncRNAs) are invol...

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Vydáno v:J Hematol Oncol
Hlavní autoři: Xiong, Guangbing, Liu, Chang, Yang, Gang, Feng, Mengyu, Xu, Jianwei, Zhao, Fangyu, You, Lei, Zhou, Li, Zheng, Lianfang, Hu, Ya, Wang, Xiaowo, Zhang, Taiping, Zhao, Yupei
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739963/
https://ncbi.nlm.nih.gov/pubmed/31514732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0777-7
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