Long noncoding RNA GSTM3TV2 upregulates LAT2 and OLR1 by competitively sponging let-7 to promote gemcitabine resistance in pancreatic cancer

BACKGROUND: Chemoresistance is one of the main causes of poor prognosis in pancreatic cancer patients. Understanding the mechanisms implicated in chemoresistance of pancreatic cancer is critical to improving patient outcomes. Recent evidences indicate that the long noncoding RNAs (lncRNAs) are invol...

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Bibliografiske detaljer
Udgivet i:J Hematol Oncol
Main Authors: Xiong, Guangbing, Liu, Chang, Yang, Gang, Feng, Mengyu, Xu, Jianwei, Zhao, Fangyu, You, Lei, Zhou, Li, Zheng, Lianfang, Hu, Ya, Wang, Xiaowo, Zhang, Taiping, Zhao, Yupei
Format: Artigo
Sprog:Inglês
Udgivet: BioMed Central 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739963/
https://ncbi.nlm.nih.gov/pubmed/31514732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13045-019-0777-7
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