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Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome

OBJECTIVE: The objective of this study is to explore the relationships of the effects of CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high platelet responsiveness (HPR) by thrombelastography in patients with acute coronary syndrome (ACS). METHODS: 459 ACS patien...

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Pubblicato in:Cardiovasc Ther
Autori principali: Peng, Wenxing, Shi, Xiujin, Xu, Xiaoyu, Lin, Yang
Natura: Artigo
Lingua:Inglês
Pubblicazione: Hindawi 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739775/
https://ncbi.nlm.nih.gov/pubmed/31772608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3470145
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