2042 CYP2C19*2 and PON1 Q192R polymorphisms are associated with platelet reactivity to clopidogrel in Puerto Rican Hispanics with cardiovascular disease

OBJECTIVES/SPECIFIC AIMS: High on-treatment platelet reactivity (HTPR) with clopidogrel imparts an increased risk for ischemic events in adults with coronary artery disease. Although more potent antiplatelet agents are available, clopidogrel remains the most commonly used P2Y12 inhibitor in Puerto R...

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Veröffentlicht in:J Clin Transl Sci
Hauptverfasser: Suarez, Dagmar F. H., Botton, Mariana R., Scott, Stuart A., Tomey, Matthew I., Melin, Kyle, Lopez-Candales, Angel, Renta, Jessicca Y., Duconge, Jorge
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cambridge University Press 2018
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Basic/Translational Science/Team Science
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6812879/
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1017/cts.2018.58
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