Both CYP2C19 and PON1 Q192R Genotypes Influence Platelet Response to Clopidogrel by Thrombelastography in Patients with Acute Coronary Syndrome

OBJECTIVE: The objective of this study is to explore the relationships of the effects of CYP2C19 and PON1 Q192R polymorphism on the activity of clopidogrel and the risk of high platelet responsiveness (HPR) by thrombelastography in patients with acute coronary syndrome (ACS). METHODS: 459 ACS patien...

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Veröffentlicht in:Cardiovasc Ther
Hauptverfasser: Peng, Wenxing, Shi, Xiujin, Xu, Xiaoyu, Lin, Yang
Format: Artigo
Sprache:Inglês
Veröffentlicht: Hindawi 2019
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739775/
https://ncbi.nlm.nih.gov/pubmed/31772608
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2019/3470145
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