Amino Acid Substitutions in Genotype 3a Hepatitis C Virus Polymerase Protein Affect Responses to Sofosbuvir

BACKGROUND & AIMS: Sofosbuvir is a frequently used pan-genotype inhibitor of hepatitis C virus (HCV) polymerase. This drug eliminates most chronic HCV infections, and resistance-associated substitutions in the polymerase are rare. However, HCV genotype 3 responds slightly less well to sofosbuvir...

詳細記述

保存先:
書誌詳細
出版年:Gastroenterology
主要な著者: Wing, Peter A.C., Jones, Meleri, Cheung, Michelle, DaSilva, Sampath, Bamford, Connor, Jason Lee, Wing-Yiu, Aranday-Cortes, Elihu, Da Silva Filipe, Ana, McLauchlan, John, Smith, David, Irving, William, Cunningham, Morven, Ansari, Azim, Barnes, Eleanor, Foster, Graham R.
フォーマット: Artigo
言語:Inglês
出版事項: W.B. Saunders 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6739484/
https://ncbi.nlm.nih.gov/pubmed/31078622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2019.05.007
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料