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Molecular basis for metabolite channeling in a ring opening enzyme of the phenylacetate degradation pathway
Substrate channeling is a mechanism for the internal transfer of hydrophobic, unstable or toxic intermediates from the active site of one enzyme to another. Such transfer has previously been described to be mediated by a hydrophobic tunnel, the use of electrostatic highways or pivoting and by confor...
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| Publicado no: | Nat Commun |
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| Main Authors: | , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group UK
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6739347/ https://ncbi.nlm.nih.gov/pubmed/31511507 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-11931-1 |
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