Biosynthesis of Tropolones in Streptomyces spp.: Interweaving Biosynthesis and Degradation of Phenylacetic Acid and Hydroxylations on the Tropone Ring

Tropolonoids are important natural products that contain a unique seven-membered aromatic tropolone core and exhibit remarkable biological activities. 3,7-Dihydroxytropolone (DHT) isolated from Streptomyces species is a multiply hydroxylated tropolone exhibiting antimicrobial, anticancer, and antivi...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Appl Environ Microbiol
Main Authors: Chen, Xuefei, Xu, Min, Lü, Jin, Xu, Jianguo, Wang, Yemin, Lin, Shuangjun, Deng, Zixin, Tao, Meifeng
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2018
Teme:
Genetics and Molecular Biology
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5981077/
https://ncbi.nlm.nih.gov/pubmed/29654178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.00349-18
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